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Reading: De novo papillary carcinoma in a thyroglossal duct cyst

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Abstracts

De novo papillary carcinoma in a thyroglossal duct cyst

Authors:

K. A. A. J. Perera ,

Sri Jayawardenapura General Hospital, LK
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S. A. Gunawardena,

Sri Jayawardenapura General Hospital, LK
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S. Rodrigo

Sri Jayawardenapura General Hospital, LK
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Abstract

Introduction

Thyroglossal duct cysts (TGDC) account for 70% of congenital neck masses.Majority (70%) is diagnosed during childhood and only 7% in adulthood.  Only 1% of thyroid carcinomas evolve from a TGDC. It’s essential to differentiate primary papillary carcinoma in a TGDC from a metastatic papillary carcinoma of thyroid.

Objective

A 23 year old girl presented with a painless lump over the anterior neck for one month. Examination revealed a non-tender firm midline neck lump just above the hyoid bone with no palpable thyroid nodules or cervical lymphadenopathy. Ultrasound revealed a suprahyoid TGDC and a sub-centimeter solitary thyroid nodule (STN) in right lobe with no cervical lymphadenopathy. FNAC of TGDC showed a benign cystic neoplasm. Ultrasound guided FNAC of the STN showed benign cells only. Thyroid functions were normal. A Sistrunk operation was performed. Histology revealed a papillary carcinoma (with CTF1 nuclear and CK19 positivity in cells lining the papillae).

A Total Thyroidectomy was performed after an oncological consultation to exclude a possible primary focus in the STN and to facilitate adjuvant treatment. Histology of the STN was a papillomatous  focus likely to be hyperplastic (CK19 negative) and rest of the thyroid normal

Conclusion

De novo papillary carcinoma in a TGDC is rare. The diagnosis in most cases is incidental after surgical resection. Total thyroidectomy would be indicated, if the carcinomatous component is > 1 cm or <1 cm but with enlarged cervical lymph nodes, tumour invasion of the cyst wall or an abnormal thyroid gland
How to Cite: Perera, K.A.A.J., Gunawardena, S.A. & Rodrigo, S., (2017). De novo papillary carcinoma in a thyroglossal duct cyst. Journal of the Postgraduate Institute of Medicine. 3, p.E 19. DOI: http://doi.org/10.4038/jpgim.8131
Published on 03 Jan 2017.
Peer Reviewed

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