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Macrophage activation syndrome – A physician’s nightmare: A case report on life threatening complication of adult-onset Still’s disease

Authors:

Sanchayan Thanancheyan ,

Teaching Hospital - Jaffna, LK
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Nisanthan Selvaratnam,

Teaching Hospital - Jaffna, LK
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Sivagamasundary Uthayakumaran,

Teaching Hospital - Jaffna, LK
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Narani Aravinthan,

Teaching Hospital - Jaffna, LK
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Thaneswary Sooriyakumar,

Teaching Hospital - Jaffna, LK
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Waruni Dissanayaka

Teaching Hospital - Jaffna, LK
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Abstract

Macrophage activation syndrome (MAS) is a subset of Haemophagocytic lymphohistiocytosis (HLH) - a rare but life-threatening multisystem disorder stemming from excessive immune system activation. Early recognition and prompt treatment are necessary to avoid numerous rapidly evolving complications. This case report describes about a young patient with adult onset stills disease evolving into MAS, who despite optimal medical management succumbed to the complications.
How to Cite: Thanancheyan, S., Selvaratnam, N., Uthayakumaran, S., Aravinthan, N., Sooriyakumar, T. and Dissanayaka, W., 2021. Macrophage activation syndrome – A physician’s nightmare: A case report on life threatening complication of adult-onset Still’s disease . Journal of the Postgraduate Institute of Medicine, 8(2), pp.E147 1–10. DOI: http://doi.org/10.4038/jpgim.8315
Published on 15 Sep 2021.
Peer Reviewed

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